Like other movies that came out around this time (1990), it captures the reality of what was happening at the time from the small perspective of these friends. It's a funny movie at times (though not a comedy), and (for me) a tear-jerker. I remember the first time I saw this film, I thought it was so remote to how my life really was, but in hindsight, I was just oblivious to what was going on.
Great acting, good storyline, and not focused on the actual disease (like And the Band Played On), more focusing on the relationships that are affected because of the disease's impact. The cast includes Bruce Davison, Dermot Mulroney and Mary-Louise Parker (this was her first film).